Curriculum Vitae

Education

1990-1994 Queen’s University Belfast, Northern Ireland
Biological Sciences B.Sc. (Hons) First Class
1994-1997 The Queen’s University of Belfast, Northern Ireland
Doctoral Degree (PhD)

Employment

2010 - present  Assistant Professor, Lawrence University, Appleton, WI.
2007 - 2010 Visiting Assistant Professor, Lawrence University, Appleton, WI.
2007 Lecturer of Parasitology, Institute of Biological Sciences, University of Wales, Aberystwyth.
2003-2006 Academic Staff – Assistant Researcher, Department of Pathobiological Sciences, UW-Madison. 
2002-2003 Postdoctoral Research Associate, Department of Biomedical Sciences, Iowa State University.
1998-2001 Postdoctoral Research Associate, Department of Pathobiological Sciences, UW-Madison.
1997-1998 Research Assistant, Department of Haematology, Belfast City Hospital, Belfast, Northern Ireland.

Research Experience

2007 - present Department of Biology, Lawrence University, Appleton, Wisconsin.
       Regulation of immune-related gene expression in the snail Biomphalaria glabrata, intermediate host of the trematode parasite Schistosoma mansoni.
2003-2006 Assistant Researcher, Department of Pathobiological Sciences, University of Wisconsin-Madison, Wisconsin.
       Signal transduction proteins and receptors involved in the regulation of B. glabrata immune responses.
2002–2003 Postdoctoral Research, Department of Biomedical Sciences, Iowa State University, Ames, Iowa.
       Structure and function of neuropeptide F and G-protein coupled receptors in S. mansoni.
1998-2001 Postdoctoral Research, Department of Pathobiological Sciences, University of Wisconsin-Madison, Wisconsin.
       Signal transduction pathways involved in the adhesion and spreading of B. glabrata cells.
1997-1998 Department of Haematology, Belfast City Hospital, Northern Ireland.
       Isolation and cryopreservation of peritoneal macrophages from the dialyses of continuous ambulatory peritoneal dialysis patients.
1994-1996 PhD research, School of Biology and Biochemistry, The Queen’s University of Belfast, Northern Ireland.
     Characterization of the nervous systems of life cycle stages of the enteric parasite, Echinostoma caproni ; neuromuscular physiology of adult E. caproni ; immunological and physiological changes in E. caproni –infected mice.

Awards

2012  Mielke Foundation award with Bart De Stasio – awarded to fund student summer research ($5000)
2008  Excellence in Science Fund, Lawrence University – awarded to fund student research ($6,000)
2007  Research Grant from the Royal Society of London, United Kingdom (₤15,000)
2007  University Research Grant, University of Wales, Aberystwyth, Wales, United  Kingdom (₤6,000)
2006  Academic Staff Professional Development grant – awarded to allow attendance at the 11th International Congress of Parasitology (ICOPA XI) meeting in Glasgow UK, August 2006
2005 Keystone Symposia Travel scholarship – awarded for travel and lodging expenses incurred while attending Molecular Helminthology: An integrated approach – Keystone Symposia
1997 Emily Sarah Montgomery Travel scholarship – awarded for travel to American Society of Parasitology Annual Meeting, Nashville, USA
1994 Hugh Wisnom Award – awarded for obtaining First Class Honors degree

Presentations at scientific meetings

Oral presentations have included:

2012  The Twelfth Congress of the International Society for Developmental and Comparative Immunology
2006   The Eleventh International Congress of Parasitology Meeting
2002  The Tenth International Congress of Parasitology Meeting
1999, 2000, 2005 Annual meetings of the American Society of Tropical Medicine and Hygiene
1997, 1999, 2013 Annual meetings of the American Society of Parasitologists
1996-1998, 2007 Annual meetings of the British Society for Parasitology

Poster presentations at:

2009  Annual meeting of the American Society of Parasitologists
2001, 2005 Molecular Helminthology: An integrated approach – Keystone Symposia
1995  Annual meeting of the British Society for Parasitology

Publications

Humphries, J.E. (2010) Effects of larval schistosomes on Biomphalaria snails. In Fried, B. and Toledo, R. (ed) Biomphalaria and larval trematodes. Springer, Heidelberg.

Humphries, J.E. and Yoshino, T.P. (2008). Regulation of hydrogen peroxide release in circulating hemocytes of the planorbid snail Biomphalaria glabrata. Developmental and Comparative Immunology, 32: 554-562.

Omar, H. H., Humphries, J. E., Larsen, M. J., Kubiak, T. M., Geary, T. G., Maule, A. G., M.J. Kimber, M. J. and Day, T. A. (2006). Identification of a platyhelminth neuropeptide receptor. International Journal for Parasitology, 37(7): 725-733. 

Humphries, J. E. and Yoshino, T.P. (2006). Schistosoma mansoni excretory-secretory products stimulate a p38 signaling pathway in Biomphalaria glabrata embryonic (Bge) cells. International Journal for Parasitology 36: 37-46.

Yoshino, T. P., Vermeire, J. J. and Humphries, J. E. (2005). Signal transduction at the host-parasite interface. In: Parasitic flatworms: Molecular Biology, Biochemistry, Immunology and Physiology. (ed. A. G. Maule and N. J. Marks) CAB International.

Vermeire, J. J., Humphries, J. E. and Yoshino, T. P. (2005). Signal transduction in larval trematodes: putative systems associated with regulating larval motility and behavior. Parasitology, 131 Suppl: S57-70. 

Humphries, J. E., Kimber, M. J., Barton, Yi-Wen, Hsu, W., Marks, N. J., Greer, B., Harriott, Maule, A. G., and Day, T. A. (2004). Structure and Bioactivity of Neuropeptide F from the Human Parasites Schistosoma mansoni and Schistosoma japonicum. Journal of Biological Chemistry 279: 39880 – 39885.

Humphries, J. E. and Yoshino, T. P. (2002). Cellular receptors and signal transduction in molluscan hemocytes: connections with the innate immune system of vertebrates. Integrative and Comparative Biology, 43(2): 305-312.

Yoshino, T. P., Boyle, J. P. & Humphries, J. E. (2001). Receptor-ligand interactions and cellular signalling at the host-parasite interface. Parasitology, 123 Suppl: S143-57.

Humphries, J. E., Elizondo, L. and Yoshino, T. P. (2001). Protein kinase C regulation of cell spreading in the molluscan Biomphalaria glabrata embryonic (Bge) cell line. Biochimica et Biophysica Acta, 1540(3): 243-52.

Humphries, J. E., Mousley, A., Halton, D. W., Maule, A. G., & Halton, D. W. (2000). Neuromusculature – structure and functional correlates. In: Echinostomes as experimental models for biological research. (ed. B. Fried & T. Grazyck). Kluwer Academic publishers, Boston.

Humphries, J. E., Corr, B., Alexander, H. D., Mc Connell, J., Bell, A. L., Markey, G. M. & Morris, T. C. (1999). Why discard the peritoneal macrophages of patients on CAPD? British Journal of Haematology, 105(1): 319-20.

Humphries, J. E., Reddy, A. and Fried, B. (1997). Infectivity and growth of Echinostoma revolutum (Froelich, 1802) in the domestic chick. International Journal for Parasitology 27(1): 129-30.

Humphries, J. E., Halton, D. W., Johnston, R. N., Maule, A. G., Johnston, C. F. & Shaw, C. (1997). Cholinergic, serotoninergic and peptidergic components of the nervous system of Haematoloechus medioplexus (Trematoda: Digenea), characterised by cytochemistry. International Journal for Parasitology 27: 517-525.

Humphries, J. E. & Fried, B. (1996). Histological and histochemical studies on the paraesophageal glands in cercariae and metacercariae of Echinostoma revolutum and E. trivolvis. Journal of Helminthology 70: 299-301.

 

 

 

 

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